摘要
老年黄斑变性(Senile Macular Degener-ation,SMD)是西方国家50岁以上老年人低视力和盲目的首要原因,目前本病在我国发病率有逐渐增高趋势。已有学者对SMD视功能改变进行多方面的研究,发现SMD早期已有色觉功能改变,并与病情的严重程度有关。本文采用Humphrey 视野分析仪黄斑色阈值程序对103例(121眼)SMD病人,其中视力或矫正视力≥1.0以上早期SMD 64例(82眼)进行了颜色明度敏感性(Color Brightness Sensitivity,CBS)检测,试图观察SMD 的CBS 改变,以探索SMD 的早期诊断方法。
In this study,the macular color threshold program of Humphrey Field Analyzer wose usedfor measuring the 64 patients (82 eyes) with early senile macular degeneration (SMD) andthe 39 cases (39 eyes) with advanced SMD and normal (82 eyes) as a control group.EarlySMD patients were 1.0 or better in visual acuity.The results that the color brightness sensitivity (CBS) of the patients with early SMD as compared with that of the normal subject decreased markedly,the difference between the groups being highly significant statistically (P<0.0001).It aslo showed that the difference between the CBS of the patients with advancedSMD had more effects than that of patients early SMD,the CBS of wet form and that of dryform had highly statistical significance.The authors suggest that this method is useful forearly diagnosis of SMD.