持续静脉滴注尼莫地平对颅内压的影响

Influence of continued intravenous perfusion of nimodipine upon the intracranial pressure

目的 探讨持续静脉滴注尼莫地平(nimodipine)对颅内压的影响;方法:对脑外伤患者术后分组(实验组—尼莫地平滴注和常规组)进行持续性ICP监测;结果:脑外伤患者ICP明显增高,经尼莫地平治疗后ICP逐步下降,并稳定在一个较低水平,无“反跳”现象;结论:尼莫地平在利尿、脱水剂的配合下,能使ICP下降,对救治脑外伤有确切疗效。

Objective: To find out the influence of continued intravenous perfusiong of nimodipine upon the intracranial pressure. Method: Persistent ICP monitoring was made on the patients of brain trauma grouped after operation (experimental group - intravenous perfusing nimodipine and control group). Results: ICP of the patients of brain trauma rose obviously but descended gradually after treatment with nimodipine and stabilized on a lower level without'bounce'appearance. Conclusion: Nimodipine can decline ICP com-lined with diuretics and dehydrant . It has reliable effect on brain trauma.