摘要
目的 :正交试验法研究利用穿山龙提取薯蓣皂苷元的生产工艺。方法 :采用水解原位萃取法 ,以薯蓣皂苷元得率为指标 ,确定了最佳工艺 ,并将该工艺与传统工艺相比较。结果 :穿山龙用含约 1.5mol·L-1硫酸的75 %异丙醇水溶液在沸水浴中加热回流提取 4 .5h ,其提取效果最佳 ,优于传统工艺。结论 :该工艺薯蓣皂苷元得率高 ,成本低 ,操作简单 ,实用性好。
Objective: To study the production technology of extraction in combination hydrolysis in situ for isolating diosgenin from Dioscorea nipponica by orthogonal design. Method: The optimum production conditions were investigated with the recovery of diosgenin as an index by extraction in combination hydrolysis in situ, and were compared with the traditional method. Result: Extraction in combination hydrolysis in situ conducted in 1.5 mol·L -1 sulfuric acid of water containing 75% isopropanol at 100 ℃ for 4.5 h could get higher recovery of diosgenin than traditional methods. Conclusion: This production technology can get higher recovery of diosgenin, and it is simple, time and money saving.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2003年第10期934-937,共4页
China Journal of Chinese Materia Medica
关键词
水解原位萃取
薯蓣皂苷元
工艺条件
穿山龙
正交试验法
extraction in combination hydrolysis in situ
diosgenin
production condition
Dioscorea nipponica
orthogonal design
