摘要
本文综述以阿尔茨海默病(Alzheimer's disease,AD)为代表的痴呆疾病的中枢神经系统乙酰胆碱、苯二氮卓类、5-羟色胺、多巴胺及组胺等递质的受体及受体亚型水平的PET/SPECT显像的临床研究进展,揭示PET/SPECT受体显像在AD的病因、病理机制、早期诊断以及药物评价等研究方面的作用,并且对该领域的研究方向提供一些建议。
Many PET/SPECT investigations have demonstrated that there are abnormities in some transmitter and receptor systems in the CNS of Alzheimer's Disease, such as acetylcholine, benzodiazepine, 5-serotonin, dopamine and histamine, etc.. Here,we introduce these progression and development directions in respect of clinical PET/SPECT studies, which may be useful in the studies of AD's etiology, pathology, early diagnosis and drug evaluation.
出处
《中华神经医学杂志》
CAS
CSCD
2003年第6期465-467,共3页
Chinese Journal of Neuromedicine
