槟榔承气汤治疗猪带绦虫病548例临床疗效及绦虫头节的电镜观察

Clinical study and electron microscope observation of tapeworm scolices on 548 cases of taeniasis treated with Binlang Chengqi Decoction

目的 观察槟榔承气汤治疗猪带绦虫病的效果及作用机制。方法 用槟榔承气汤治疗绦虫病 5 4 8例 ,并对驱出的10例绦虫头节做了电镜观察。结果 治愈 5 2 1例 ,好转 2 7例 ,总有效率 10 0 %。扫描电镜见绦虫头节吸盘内有泡状分泌物 ,颈部上皮糜烂 ;透射电镜见皮层严重受损 ,微毛脱落 ,肌层及实质层细胞均有不同程度损伤 ,线粒体肿胀或空变 ,神经索受损。结论 槟榔承气汤对绦虫头节不仅有神经麻痹作用 ,对其组织细胞也有明显损伤作用。

Objective To observe the effect and mechanism of Chinese herbs in the treatment of taeniasis. Methods Five hundred and forty eight cases of taeniasis were treated with Binlang Chengqi Decoction(BLCQD).The tapeworm scolices of ten cases were observed by electron microscope (EM). Results Among the 548 cases, 521 cases were cured and 27 cases were improved. The total effective rate was 100%. Foam like secretion in the sucker of the tapeworm scolices and erosion of the epithelium in the cervical part were observed by scanning electron microscope. Observed by transmission electron microscope, the cortex was seriously damaged.The microvilli were exfoliated.The cells in the muscle layer and parenchyma layer were injured in various degrees.The mitochondria were tumefied or caved.And the nerve cord was damaged. Conclusion BLCQD can not only paralyze the tapeworm scolex,but also injury the cells of the tapeworm scolex.