新型钙离子拮抗剂尼伐地平

Nilvadipine a New Calcium Ion Antagonist

尼伐地平属于第二代二氢吡啶类钙离子拮抗剂 ,其与Ca2 + 通道特异部位的结合力比硝苯地平强 10倍 ,作用持续时间较之长 2～ 3倍 ,血药浓度较为平稳 ,良好的降压作用能维持 2 4h以上。因此 ,尼伐地平是安全、有效的首选高血压治疗药物 ,其应用前景十分广阔 ,市场潜力十分巨大。

Nilvadipine is the second generation of dihydropyridine calcium ion antagonist. Its cohesion with the special location of calcium ion is 10 times stronger than previous Nifedipine with lasting 2 to 3 times longer. The blood pressure decreasing effect can be maintained well for 24 hours because of its steady pharmaceutical concentration in blood. So Nilvadipine is a safe, efficacious and first-selective pharmaceutical in treatment of hypertension. Hence it has a wild potential in the market.