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益生菌LGG的研究 被引量:3

Review on studies of probiotics
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摘要 LGG(ATCC53103)是一种专利的鼠李糖乳杆菌,八十年代初由两位美国教授从健康人体内分离而得,也是目前全球研究最多的益生菌之一。大量的体外实验、动物实验、人体实验和流行病学调查研究充分证明了LGG的安全性。功能性方面,LGG具有显著的平衡和改善肠道菌群、预防和治疗腹泻、提高机体免疫力、预防过敏、结合并排除毒素、预防龋齿等功能。此外,作为一种益生菌,LGG还具有一些自身的优势:比如耐胃酸、耐胆汁、可定殖于人体肠道、最终产品(酸奶、牛奶等)保质期内活菌数保持恒定等。 LGG, a patented L. rhamnosus strain (ATCC 53103), was discovered from healthy person by two American professors in early 1980抯. It is the best documentated probiotics in the world. The safety of LGG is verified by many in vitro experiments, animal studies, clinical studies and epidemiological studies. Its functionalities include: improving GI tract function, preventing and cure diarrhea, regulating immune function, preventing allergies, binding and eliminating toxins, preventing dental caries, etc. In addition, compared with many other probiotics, LGG has a lot of advantages, such as it can survive in low pH environment, colonize in GI tract, live LGG remains almost constant in final products during shelf life, etc.
出处 《广州食品工业科技》 2003年第B11期55-58,70,共5页
关键词 益生菌 LGG 安全性 功能性 乳杆菌 probiotics LGG safety functionality advantage
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  • 1Benno, Y., HE, E, et al. 1996. Effect of Lactobacillus GG yoghurt on human intestinal microecology in Japanesesubjects. Nutrition Today 31 (6) Suppl. 1: 9S-11S.
  • 2Donohue DC, Deighton M, Ahokas JT, Salminen S (1993)Toxicity of lactic acid bacteria.307-313.
  • 3El-Nezami, H.,et al. 1998 a. Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1.Food Chem. Toxicol. 36: 321-326.
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  • 6Gupta P, Andrew H, Kirschner BS, Guandalini S (2000) Is lactobacillus GG helpful in children with Crohn's disease?Results of a preliminary, open-label study. J Pediatr Gastroenterol Nutr 31:453-7.
  • 7Hilton E, Kolakowske P, Smith M and Singer C: 1997.Efficacy of Lactobacillus GG as a diarrheal preventative in travellers. J Travel Med 4: 41-43.
  • 8Hudault, S.,et al. 1997. Antagonistic activity excerted in vitro and in vivo by Laetobacillus casei (strain GG) against Salmonella typhimurium C5 infection. Appl. Environ.Microbiol. 63:513-518.
  • 9Jukka Meurman et al. 2000. LGG offers dental care. LGG Action. 2:10-11
  • 10Kaila, M, Isolauri, E., et al. 1998. Fecal recovery of a human Laetobacillus strain (ATCC 53103) during dietary therapy of rotavirtts diarrhea in infants. Biosci. Microflora 17 (2): 149.

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