固载杂多酸树脂催化合成苯甲醛正己硫醇缩醛

Synthesis of benzaldehyde hexyl mercaptal spice on supported heteropolyacid catalyst

以离子交换树脂固载磷钨酸为催化剂合成了苯甲醛正己硫醇缩醛。在考察了各种影响收率因素的基础上,得出最优工艺条件为:n(苯甲醛)∶n(正己硫醇)∶m(催化剂)∶V(二氯甲烷)=1mol∶2 15mol∶20g∶350ml,43℃,回流,反应时间5 0h。在此条件下收率可达86 3%。催化剂可重复使用。

Benzaldehyde hexyl mercaptal was synthesized using phosphotungstic acid supported on cationic exchange resin as the catalyst .The factors affecting the condensation yield were investigated. The results showed that the optimum conditions are as follows: benzaldehyde∶hexyl mercaptan∶catalyst∶dichloromethane=1mol∶215mol∶20g∶350ml; reaction temperature 43℃,reflux,reaction time 50 h. Yield of over 863% was obtained under the optimum condition. The catalyst can be used repeatedly.