1007例急性胰腺炎病因分析

Analyse on Etiology of 1007 Patients with Acute Pancreatitis

目的 :探讨急性胰腺炎的病因 ,旨在提高对急性胰腺炎发病因素的认识。方法 :回顾性分析我院自 1 992年 1月至 2 0 0 1年 1 2月的内外科住院急性胰腺炎患者 1 0 0 7例。对其发病因素进行分析。结果 :急性胰腺炎发病例数逐年增多 ,1 992年至 1 996年间病例数占同期内外科住院总人数的 0 .36% ,而 1 997年至 2 0 0 1年间则上升为 0 .59% ,两者差异有显著性意义 (P <0 .0 1 )。其中不明原因者所占比例亦呈上升趋势。1 992年至 1 996年间不明原因的急性胰腺炎占同期急性胰腺炎总例数的 1 6 .8% ,1 997年至 2 0 0 1年则上升为32 .9% ,两者差异有显著性意义 (P <0 .0 1 )。月份分布情况表明 ,急性胰腺炎发病呈明显集中趋势 ,月份分布不平衡。结论 :急性胰腺炎发病因素多而复杂 。

Purpose: Our goal was to explore the etiology and pathogenesis of acute pancreatitis and to enhance the knowledgement of its pathogenesis. Methods: 1 007 patients with acute pancreatitis were admitted to our hospital from January 1992 to December 2001.We reviewed the clinical data to analyse the pathogenesis of acute pancreatitis. Results: The patients of acute pancreatitis increased year and year.The acute pancreatitis rates ranged from 0.36%(1992～1996) to 0.59%(1997～2001),with signifinicant differences (P<0.01).Of all acute pancreatitis,the unconfimed cases had increased:16.8% patients with acute pancreatitis from 1992 to 1996 versus 32.9% ones from 1997 to 2001,with signifinicant differences (P<0.01).The distribution of month indicates that the currence of acute pancreatitis is obviously convergent and the distribution of month is of no balance. Conclusion: The pathogenesis of acute pancreatitis is excessive and complicated.Virus infection may be one of the factors that lead to the increase of acute pancreatitis.