超声引导经皮集束电极射频消融冶疗中小肝癌

Percutaneous Ultrasound Guided Cluster Electrode Radiofrequency Ablation of Medium and Small Hepatocarcinoma

目的 :探讨超声引导经皮集束电极射频消融 (RFA)治疗中小肝癌 (直径≤ 5cm)的疗效。方法 :利用RF 2 0 0 0 TM肿癌射频治疗系统 ,在B超引导下对 2 9例中小肝癌患者 34个肿块进行经皮肝穿刺射频热凝冶疗 ,并用B超及CT检查以了解RFA治疗效果 ,随访观察其复发和生存情况。结果 :RFA治疗后 93 3 % (2 8/30 )的肿块血供消失 (另 4个直径≤ 3cm的肿块治疗前即无血供 ) ,且 94 1 % (32 /34)的肿块呈完全凝固性坏死。对有血供的 2个肿块再次进行了RFA治疗。随防 6月～ 3年 ,2 9例中现存活 2 5例 ,半年生存率 1 0 0 %。存活的 2 5例中 ,已有 6例生存半年 ,7例生存 1年 ,7例生存 2年 ,5例生存 3年。结论 :集束电极RFA治疗中小肝癌创伤小 ,安全 。

Purpose: To evaluate the therapeutic efficacy of percutaneous cluster electrode radiofrequency ablation(RFA) to treat medium and small hepatocarcinoma(diameter≤5 cm). Methods: 29 patients with histologically confirmed medium and small primary hepatocarcinoma were treated percutaneously under ultrasound guidance using RF-2000 TM cluster electrode radiofrequency ablation system.29 patients had 34 tumors. Ultrasound and CT were also used to evaluate the blood supply coagulation necrosis in the treated tumors.All cases had been followed up for at least 6 months to 3 years. Results: Blood supply of tumors was disappeared in 93.3%(28/30)after RFA treatment(another 4 tumors without blood supply before RFA).Complete coagulation necrosis was seen in 94.1% tumors(32/34).The 2 tumors which still had blood supply were treated again with RFA. 25 of 29 cases survived during the subsequent following up of 6 months to 3 years. Survival rate for half a year was 100%. 6 cases were survival for 6 months, 7 for 1 year,7 for 2 years and 5 for 3 years. Conclusion: RFA is minimally invasive,safe and effective for the treatment of medium and small hepatocarcinoma.