摘要
药物分子的立体化学决定其生物活性 ,手性已成为药物研究的一个关键因素。利用微生物或酶催化的方法进行手性化合物的不对称合成已经成为一个极具吸引力的方向。综述了近年来利用面包酵母催化不对称合成手性化合物的研究进展 ,着重讨论了利用面包酵母可进行的多种手性试剂的催化合成的反应类型。
As stereochemistry in drug molecule govern it's biological activity,chirality is emerging as a key issue in pharmaceutical research.It has become attractive to asymmetrically synthesize of chiral reagent through biotransformations. This review covers the application of baker's yeast to the asymmetric synthesis of chiral reagent. The types of catalytic synthesizing chiral reagent by using baker's yeast were introduced.
出处
《天津化工》
CAS
2003年第6期10-13,共4页
Tianjin Chemical Industry
关键词
面包酵母
不对称合成
手性化合物
baker's yeast
asymmetric synthesis
chiral reagent
