水盐限制对糖尿病腹膜透析患者容量负荷状况的影响

Effect of salt and water restriction on fluid status in diabetic peritoneal dialysis patients

目的 探讨限制水盐摄入对糖尿病腹膜透析患者容量负荷状况的影响。方法 采用自身前后对照的方法调查所有接受连续性不卧床腹膜透析 (CAPD)治疗至少 6个月以上的糖尿病肾病患者 ,严格限制水、盐摄入。评估并检测水盐限制前及水盐限制 1～ 3个月后容量负荷、体重、平均动脉压和超滤量等变化。结果 2 0 0 2年 5月～ 10月间 2 0例糖尿病肾病CAPD患者 ,水盐限制前水肿程度、体重、平均动脉压、空腹血糖、透析液糖浓度、透析液糖总量、透析液总剂量和平均超滤量及总清除量均大于水盐控制后 ,差异均有显著性 ;水盐限制前后患者的尿量无明显变化。结论 单纯限制水盐摄入能明显改善糖尿病CAPD患者容量超负荷状况 ,并能降低血压。

Objective To study the effect of salt and water restriction on fluid status in diabetic peritoneal dialysis patients.Methods In a self-controlled study,20 diabetic patients treated with peritoneal dialysis for at least 6 months were investigated.The patients were advised to take salt and water restriction and were followed up for 1～3 months.Results After restricting salt and water intake,edema,body weights,mean arterial pressure,fasting blood glucose,dialysate doses,dialysate glucose load,peritoneal ultra filtration and total fluid removal were significantly decreased,whereas the urine volume did not change significantly.Conclusions Restricting salt and water intake may be effectively used to treat fluid overload in diabetic patients with peritoneal dialysis and facilitates the blood glucose and blood pressure control.