不稳定性心绞痛患者冠状动脉内支架术的临床疗效评价

Clinical Evaluation of the Treatment Effectiveness of Coronary Stenting in Patients with Unstable Angina Pectoris

目的：评价冠状动脉内支架术治疗不稳定性心绞痛的疗效及安全性。方法：用冠状动脉内支架术治疗３８例不稳定性心绞痛（ＵＡＰ）患者及１８ 例稳定性心绞痛（ＳＡＰ）患者。结果：ＵＡＰ组和ＳＡＰ组均有很高的手术成功率，分别为９４．７％ 及１００％ （Ｐ＞ ０．０５）。２ 例ＵＡＰ患者发生急性心肌梗塞，其中１例与冠状动脉内支架血栓形成有关，无死亡病例。所有手术成功的患者心绞痛症状明显缓解或消失。平均随访１１±６个月，有５ 例在术后２～５个月再发心绞痛，其中ＵＡＰ患者４ 例及ＳＡＰ患者１ 例，均经冠状动脉造影证实为再狭窄，并再次行经皮冠状动脉腔内成形术治疗成功。结论：初步认为冠状动脉内支架术对ＵＡＰ患者是一种安全有效的治疗措施。

Objective:To evaluate the treatment effectiveness and safety of coronary stenting in patients with unstable angina pectoris (UAP).Methods:Coronary stenting was used to treat 38 patients with UAP and 18 patients with stable angina pectoris (SAP).Results:In both groups,coronary stenting presented a high procedural success rate.The procedural success rates were 94.7% in UAP group and 100% in SAP group ( P >0.05).The anginal symptoms were relieved or disappeared in the succesful patients.Acute myocardial infarction occurred in 2 patients with UAP and was related to stent thrombosis in one.No death occurred.At 11±6 months follow up,five cases had chest pain again between 2 to 5 months after stenting.Restenosis was confirmed by angiography and repeated by PTCA in 4 patients (10.5%) with UAP and in 1 patient (5.6%) with SAP ( P >0.05).Conclusion:These findings suggest preliminarily that coronary stenting for UAP is a safe and effective interventional procedure.It is also necessary to prevent stent thrombosis from happening.