富糖原型宫颈腺癌与乳头瘤病毒-18的相关性研究

Asso ciation between glycogen - rich carcinoma of the cervix and human papillomavirus - 18

目的:研究乳头瘤病毒-18与富糖原型宫颈腺癌的关系.方法:根据组织化学染色,选择了10例富糖原型宫颈腺癌,采用PCR法分析其中的乳头瘤病毒(HPV),并对临床资料进行分析.结果:7例富糖原型宫颈腺癌呈现HPV-18DNA阳性,8例患者有复发并死于子宫颈癌.结论:富糖原型宫颈腺癌是一类与HPV-18相关的进行性癌.

Objective: To study the association between glycogen - rich adeno carcinoma of the cervix and human papillo-mavirus- 18(HPV- 18) . Methods:Ten cases of glycogen- rich cervical adenocarcinoma were analyzed by using polymerase chain re-action(PCR) - Results:7 patients with glycogen ?rich adenocarcinoma showed HPV?18 DNA positive. 8 patients have developed re-current disease and die of their cervical tumors. Conclusion:glycogen ?rich adenocarcinoma of the cervix is associated with HPV?18 and has an aggressive clinical course.