人脑侵袭性垂体腺瘤的生物学活性

The biological characters of invasive pituitary adenoma of human.

目的 侵袭是恶性肿瘤的生物学特征,而部分人脑垂体腺瘤也具有.本实验研究该类腺瘤细胞DNA倍体特征和增殖活性.方法:通过流式细胞术和细胞图像分析技术检测.结果:垂体腺瘤侵袭性和异常DNA倍体垂体腺瘤细胞比例相关密切.结论:从细胞DNA倍体角度分析,侵袭性垂体腺瘤具有恶性生长倾向.

Objective: Invasive is the feature of malignancy tumor, which some pituitary adenomas have. The DNA ploidy and proliferation ability of invasive adenoma cell were studied. Methods: Pituitary adenoma cells were assayed by Flow Cytometer and Image Cytometer. Results: Invasive of pituitary adenoma correlate to the proportion of abnormal DNA ploidy cell. Conclusions: From the DNA ploidy of invasive pituitary adenoma, it can be conclude that invasive pituitary adenoma is getting to develop malignantly.