阴茎癌149例临床分析

Diagnosis and treatment of penile cancer:a report of 149 cases

目的:探讨阴茎癌的诊断与治疗方法。方法:回顾性分析2000年1月~2014年12月收治149例阴茎癌患者的临床资料。结果:149例中鳞状细胞癌121例,乳头状瘤恶变13例,疣状癌9例,Paget病4例,恶性黑色素瘤2例。行阴茎部分切除术115例,阴茎全切加会阴部尿道造口术22例,腹股沟淋巴结清扫术34例。129例患者定期随访1~10年,1、2、5、10年总体生存率分别为94.2%(121/129)、90.5%(116/129)、78.3%(101/129)、17.8%(23/129)。结论:外科手术是治疗阴茎癌合理有效的方法,淋巴结转移是影响阴茎癌预后的重要因素。合理的选择腹股沟淋巴结清扫术的时机,可改善预后并减少并发症的发生。

Objective:To investigate reasonable and effective diagnosis and treatment of penile cancer.Methods:The clinical data of 149 patients with penile cancer treated from January 2000 to December 2014 were analyzed retrospectively.Results:There were 121 cases of squamous cell carcinoma,13 cases of malignant change of papilloma,9cases of verrucous carcinoma,4cases of Paget disease,and 2cases of malignant melanoma.115 cases received partial penectomy,22 cases received total penectomy and perineal urethrostomy,and 34 cases received inguinal lymphadenectomy.129 cases were regularly followed up for 1to 15 years.The 1-,2-,5-and 10-year survival rate were94.2%(121/129),90.5%(116/129),78.3%(101/129)and 17.8%(23/129)respectively.Conclusions:Partial penectomy is an appropriate and effective management for penile cancer.Lymph node metastasis is an important prognostic factor for penile cancer.We could significantly increase the survival rate of patients and reduce the complications by selecting reasonable inguinal lymphadenectomy timing.