经尿道前列腺分叶剜除术与电切术治疗大体积前列腺增生症的比较研究

Divided lobectomy of transurethral enucleation of prostate and transurethral resection of prostate for large volume benign prostatic hyperplasia

目的:研究经尿道前列腺分叶剜除术(TUEP)和经尿道前列腺电切术(TURP)治疗大体积前列腺增生症(BPH)的安全性和有效性。方法:回顾性分析168例BPH患者临床资料(前列腺体积大于80ml),分为TUEP组(68例)和TURP组(100例),比较两组手术时间、术后IPSS、QOL评分、最大尿流率(Q_(max))、膀胱剩余尿变化及术后相关并发症。结果:TUEP组较TURP组手术时间缩短(P<0.05),但两组术后IPSS评分、QOL评分、Q_(max)、膀胱剩余尿变化及术后并发症差异无统计学意义(P>0.05)。术后1、3个月两组IPSS、QOL、Qmax、膀胱剩余尿均较术前明显改善。结论:分叶TUEP术治疗大体积BPH能够取得与TURP相当的疗效,是治疗大体积BPH安全有效的手术方式之一。

Objective:To evaluate the safety and effectiveness of divided lobectomy of transurethral enucleation of prostate(TUEP)and transurethral resection of prostate(TURP)for large volume benign prostatic hyperplasia.Methods:A retrospective analysis of the clinical data of 168 BPH patients with prostate volume lager than 80 mL was performed,and 168 BPH patients were divided to TUEP group(n=68)and TURP group(n=100).Comparisons were made between two groups in operating time,International Prostate Symptom Score(IPSS),quality of life(QOL),maximum urine flow rate(Qmax),residual urine volume and adverse events.Results:As compared with TURP group,the operating time was significantly shortened in TUEP group(P<0.05).However,there were no statistically significant differences between two groups in IPSS,QOL,Qmaxand residual urine volume(P>0.05).Meanwhile,IPSS,QOL,Qmaxand residual urine volume were significantly improved in TUEP and TURP groups postoperation as compared with those preoperation.Conclusions:Divided lobectomy of TUEP and TURP are equally effective procedure for larger BPH.Therefore,divided lobectomy of TUEP is a safe and effective method for large volume benign prostatic hyperplasia.