呼吸机相关性肺炎相关因素分析

Retrospective Study on Correlation Factor of Ventilator-Associated Pneumonia

目的 通过回顾分析呼吸机相关性肺炎 (VAP)患者的临床资料及相关因素 ,提高对 VAP的认识。方法 收集 1999年 9月至 2 0 0 3年 9月入住我院 ICU行机械通气患者的临床资料 ,按诊断标准分为发生 VAP组和未发生VAP组 ,对两组患者的相关因素及预后进行评价。结果 共收集 14 1例次 ,发生 VAP组 78例次 ,未发生 VAP组 6 3例次 ,发生 VAP组机械通气时间明显长于未发生 VAP组 (P<0 .0 5 ) ;两组在年龄、APACHE 评分相仿 ,而病死率却无差别 (P>0 .0 5 ) ,预防性使用抗生素不能降低 VAP的发生。结论 VAP不是导致患者死亡的直接原因 ,而是病情为重的一个表现。防治 VAP的措施仍应采用。

Objective To deepen the understanding about ventilator associated pneumonia(VAP).Method Patients admitted to the intensive care unit from Sep. 1999 Sep. 2003 were divided into two groups, with of without VAP, according to the diagnosis criteria. The comarative analysis was performed in clinical characteristics, correlation factor.Results The incidence of VAP was 55.32% the cases of non VAP group was 63. Patients with VAP showed longer ventilation times ( P <0.05). No difference was found for age, APACHE Ⅱ values and for mortality between patients from group 1 and 2 ( P >0.05). Prophylactic use of antimicrobials can not decrease the morbidity of VAP. Conclusions VAP was not the efficient cause of death in ICU, but only a exhibition. Preventive measures should be employed.