开郁清胃颗粒对2型糖尿病胰岛素敏感性的影响

The Effect of Kaiyu Qingwei Granule on Insulin Sensibility of Type 2 Diabetes

目的:通过临床观察初步探讨开郁清胃颗粒对2型糖尿病患者胰岛素敏感性的影响。方法:以二甲双胍为对照,观察60例2型糖尿病患者治疗前后体重及腰臀围、症状积分、血糖、胰岛素、胰岛素敏感指数、血脂、焦虑及抑郁积分等指标的变化。结果:开郁清胃颗粒对2型糖尿病患者的血糖、血脂紊乱有明显的改善作用,并能减轻体重,提高胰岛素敏感性,改善焦虑及抑郁状态。结论:开郁清胃颗粒增加2型糖尿病患者的胰岛素敏感性可能与改善血脂紊乱,改善焦虑、抑郁状态及减轻体重等有关。

Objective: To observe the effect of Kaiyu Qingwei granule on the insulin sensibility of patients with type 2 diabetes. Method: Through the observation-comparison of Chinese medicine with Metformin, we surveyed the difference of body's weights before and after clinical experiment, integral of symptoms, insulin, insulin sensibility index, fat of blood cholesterol, anxiousness and melancholy. Result: The extract type of Kaiyu Qingwei granule curtails bloody glucose at the time of an empty stomach and after dinning, improves the replacement of cholesterol, lessens the body weights, also betters the state of anxiety and depression. Conclusion: Through improving bloody glucose, bloody cholesterol and lessening of body weights, deteriorating of IR and increasing of insulin sensibility with Chinese medicine, the total results derived from several research methods. This is the superiority that the Chinese medicine is able to cure IR.