摘要
昆虫病毒gp37 fusolin基因属病毒复制非必需基因 ,其编码的蛋白能形成一种纺锤形包涵体 (spindlebodies,SBs) ,该包涵体内不含有病毒粒子。Fusolin蛋白形成的SBs与纯化的Fusolin蛋白均能提高靶昆虫对杆状病毒的敏感性 ,推测GP37蛋白也具有类似的功能。对gp37 fusolin基因的深入研究 。
Insect baculovirus and entomopoxvirus gp37/fusolin genes are unessential in virus replication,which encode GP37/Fusolin proteins that form spindle bodies (SBs).SBs formed by Fusolin and purified Fusolin protein can improve the sensitivities of target insects to baculoviruses.It was proposed that GP37 proteins,like Fusolin,have an accessory function that is not required for viral replication and it may be possible to adapt the function of GP37/Fusolin for human advantage by using the presence of increased or alternate GP37/Fusolin proteins as “adjuvants' for viral biopesticides.
出处
《中国生物工程杂志》
CAS
CSCD
2003年第11期16-18,共3页
China Biotechnology
基金
国家"973"重点基础规划研究资助项目 (G2 0 0 0 0 162 0 9)
