中浆的眼底荧光血管造影与视觉诱发电位

A Study of the Relationship between FFA and PVEP in Central Serous Chorioretinopathy

目的探讨中心性浆液性脉络膜视网膜病变患者的荧光血管造影(FFA)与图形视觉诱发电位(PVEP)改变之间的关系。方法对中浆患者117例121眼进行FFA及PVEP检查,并按不同渗漏部位分为黄斑中心区组、旁黄斑区组和黄斑周围区组,将三组的PVEP检查结果分别与正常对照组(30例60眼)进行组间比较。结果 FFA检查发现中浆患者121眼渗漏部位于黄斑中心区为22眼;旁黄斑区75眼;黄斑周围区24眼。黄斑中心区组的P_(100)波潜伏期较正常对照组显著延长(P<0.05),振幅明显下降(P<0.05);而其他两组无论P_(100)波潜伏期或振幅与正常对照组相比差异均无显著性。结论中浆患者的P_(100)波潜伏期的延长以及振幅的下降与病变部位关系较密切。

Purpose To investigate the relationship between fundus fluorescein angiography( FFA) and pattern visual evoked potential( PVEP) in central serous chorioretinopathy. Methods The FFA and PVEP were performed on 121 eyes of 117 consecutive patients with CSC and 60 eyes of 30 healthy subjects. According to leakage position, the patients were divided three groups: foveola, parafovea and perifovea , and the results of PVEP of each patient s group and that of HS group were compared respectively. Results 22 eyes in the patients of CSC were foveola, 75 eyes were parafovea and 24 eyes were perifovea. The latency of P100 in foveola group were significantly prolonged( P < 0.05) ,and the amplitude markedly decreased compared with HS group ( P < 0.05) ;The latency and amplitude of P100 had no significant difference between other two groups and HS group. Conclusion There is a significant relationship between the latency and amplitude of P100 and the leakage position in CSC.