不同干预方式对胶囊内镜消化道转运时间的影响

Effect of Different Intervention on Gastrointestinal Tract Transit Time in Capsule Endoscopy

背景:胶囊内镜目前广泛用于小肠疾病的诊断,近年如何提高胶囊内镜全小肠检查完成率(CER)日益受到关注。目的:探讨不同干预方式在胶囊内镜检查中对胃转运时间(GTT)和小肠转运时间(SBTT)的影响。方法:选取2012年1月-2013年5月上海长海医院接受胶囊内镜检查的患者90例,随机分为对照组、右侧卧位组和运动组,吞服胶囊内镜后分别给予安静休息、右侧卧位和快步走,直至胶囊内镜通过幽门进入十二指肠。比较三组GTT、SBTT、CER和疾病诊断率。结果:与对照组相比,右侧卧位组GTT明显缩短(P<0.05),而SBTT无明显差异(P>0.05);运动组GTT、SBTT均明显缩短(P<0.05)。对照组、右侧卧位组和运动组的CER和疾病诊断率相比均无明显差异(P>0.05)。结论:右侧卧位能缩短胶囊内镜GTT,快步走能缩短胶囊内镜GTT和SBTT,两者在胶囊内镜检查中均具有较好的临床应用价值。

Background:Capsule endoscopy( CE)has been widely used for the diagnosis of small intestinal diseases. How to enhance the complete examination rate( CER)has attracted more and more attention in recent years. Aims:To investigate the effect of different intervention on gastric transit time( GTT)and small bowel transit time( SBTT)in CE. Methods:Ninety patients undergoing CE from January 2012 to May 2013 at Changhai Hospital were enrolled and randomly divided into control group,right lateral position group and motion group. The patients in control group were allowed to keep quiet, patients in right lateral position group were asked to lie on their right side,and patients in motion group were asked to take rapid pace walking after swallowing the capsule until the capsule passing pylorus. GTT,SBTT,CER and disease diagnosis rate among the three groups were compared. Results:Compared with control group,GTT was significantly decreased in right lateral position group(P﹤0. 05),however,no significant difference in SBTT was found between right lateral position group and control group(P ﹥0. 05). GTT and SBTT were both significantly decreased in motion group than in control group(P﹤0. 05). No significant differences in CER and disease diagnosis rate were found among the three groups(P﹥0. 05). Conclusions:Right lateral position can shorten GTT,rapid pace walking can shorten GTT and SBTT,and both these two intervention have substantial clinical values in CE.