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Hepatic manifestations of non-steroidal inflammatory bowel disease therapy 被引量:1

Hepatic manifestations of non-steroidal inflammatory bowel disease therapy
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摘要 Inflammatory bowel disease(IBD) is composed of Crohn's disease and ulcerative colitis and is manifested by both bowel-related and extraintestinal manifestations. Recently the number of therapeutic options available to treat IBD has dramatically increased, with each new medication having its own mechanism of action and side effect profile. A complete understanding of the hepatotoxicity of these medications is important in order to distinguish these complications from the hepatic manifestations of IBD. This review seeks to evaluate the hepatobiliary complications of non-steroid based IBD medications and aide providers in the recognition and management of these side-effects. Inflammatory bowel disease(IBD) is composed of Crohn’s disease and ulcerative colitis and is manifested by both bowel-related and extraintestinal manifestations. Recently the number of therapeutic options available to treat IBD has dramatically increased, with each new medication having its own mechanism of action and side effect profile. A complete understanding of the hepatotoxicity of these medications is important in order to distinguish these complications from the hepatic manifestations of IBD. This review seeks to evaluate the hepatobiliary complications of non-steroid based IBD medications and aide providers in the recognition and management of these side-effects.
出处 《World Journal of Hepatology》 CAS 2015年第27期2716-2728,共13页 世界肝病学杂志(英文版)(电子版)
关键词 HEPATOTOXICITY ADVERSE DRUG reactions DRUG induced Hepatotoxicity Adverse drug reactions Drug induced
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