PROSTATE CANCER BONE-METASTASIS IS INHIBITEDBY CELASTROL, AN ACTIVE CONSTITUENT OF TRIPTERYGIUM WILFORDII HOOK.F.(雷公藤)
PROSTATE CANCER BONE-METASTASIS IS INHIBITEDBY CELASTROL, AN ACTIVE CONSTITUENT OF TRIPTERYGIUM WILFORDII HOOK.F.(雷公藤)
摘要
Prostate cancer(PCa)is one of the most common malignant tumours and a leading cause of cancer deaths.Treatment failure of PCa is often due to bone-metastasis.Celastrol,an active constituent of the roots of Tripterygium wilfordii,has shown antitumour effects in previous studies in accordance with its use in TCM.Here we report for the first time an in-depth study of the effects of celastrol on
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