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430例武警新兵HLA-B27结果分析

Results of HLA-B27 detection in 430 recruits of People's Armed Police Force
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摘要 目的了解武警部队新兵HLA-B27阳性率情况,探讨其检测的意义。方法使用流式细胞技术,检测武警某部430例新兵的HLA-B27抗原,并对其阳性率和地方人群进行比较。结果 430例样本中HLA-B27阳性23例,阳性率5. 35%,和文献中安徽淮南市、河北邯郸市、四川达州市、广州市,以及福建泉州市的健康人群HLA-B27阳性率相比,差异无统计学意义(P> 0. 05)。结论检测入伍新兵HLA-B27,观察长期的军事训练是否更容易诱发HLA-B27阳性者患强直性脊柱炎,有助于减少部队非战斗损伤,提高部队战斗力。 Objective To investigate the significance of testing HLA-B27 in army recruits.Methods HLA-B27 antigen was detected in 430 recruits of Armed Police Force using flow cytometry.The positive rate was compared with that of the local populations.Results Flow cytometry detection showed that there were 23 positive cases in the 430 recruits,with a positive rate of 5.35%.Compared with healthy populations in Huainan of Anhui,Handan of Hebei,Dazhou of Sichuan,Guangzhou of Guangdong,and Quanzhou of Fujian,the positive rate was not significantly different(P>0.05).Conclusions Detection of HLA-B27 antigen in recruits and observing whether military training is more likely to induce ankylosing spondylitis in HLA-B27 positive soldiers will help reduce non-combat injuries and enhance the combat effectiveness of troops.
作者 段萃娟 王玉飞 凌爱琴 郭晓今 刘元明 王莉 杨晓莉 DUAN Cuijuan;WANG Yufei;LING Aiqin;GUO Xiaojin;LIU Yuanming;WANG Li;YANG Xiaoli(Department of Clinical Laboratory,the Third Medical Center of PLA General Hospital,Beijing 100039,China)
出处 《武警医学》 CAS 2019年第5期395-396,401,共3页 Medical Journal of the Chinese People's Armed Police Force
基金 武警总医院院级课题-临床类推广应用(WZ2017028)
关键词 新兵 HLA-B27 强直性脊柱炎 recruits HLA-B27 ankylosing spondylitis
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