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循环肿瘤DNA在乳腺癌诊治中应用的研究 被引量:2

Application of circulating tumor DNA in diagnosis and treatment of breast cancer
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摘要 随着乳腺癌'精准医疗'进入个体化时代,一方面需针对乳腺癌的高度异质性进行实时监测,寻找更有效的诊断、疗效和预后预测方面的指标,另一方面也需对病人肿瘤组织标本进行基因检测,指导个体化临床肿瘤综合治疗[1]。循环肿瘤DNA(circulating tumor DNA,ct DNA)检测作为一种新兴的'液体活检'技术,近来以其微创或无创、可重复、高灵敏度和特异度等优点,备受关注[2]。作为组织学基因检测的补充,ct DNA检测在肿瘤的早期诊断、肿瘤负荷监测、治疗反应和耐药预测等方面具有潜在的应用价值。本文就ct DNA检测在乳腺癌诊治方面应用的进展作一综述。
出处 《外科理论与实践》 2018年第5期473-476,共4页 Journal of Surgery Concepts & Practice
基金 上海申康医院发展中心新兴前沿技术联合攻关项目(SHDC12014103)
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