BACTEC-MGIT960快速培养药敏对肺结核诊治的应用和评价

Evaluation of the application for fast cultivation an d drug susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis

目的 BACTEC MGIT960快速培养药敏在肺结核诊治中的应用评价。方法 采用BACTEC MGIT960进行快速培养药敏 ,并与改良罗氏培养基和改良 7H9培养基进行比较。结果 BACTEC MGIT960培养报告时间仅 8.5d ,明显短于改良 7H9培养基 (2 0 .6d)和改良罗氏培养基 (30 .8d)。BACTEC MGIT960药物敏感试验结果与其它检测方法相比 ,符合率在 90 %以上 ,平均报告时间仅 6.5d,明显短于改良 7H9培养基 (1 7d)和改良罗氏培养基(2 6 .5d)。结论 BACTEC MGIT960快速培养药敏有助于肺结核的诊断和治疗 ,是一种快速、有效。

Objective To evaluate the application for fast c ul tivation and susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis.Methods Fast cultivation of mycobactria tuberculous and suscept ibility tests by BACTEC-MGIT960 and compared with improved 7H9 drug medium and improved L-J medium.Results Average report time of cultivation and drug susceptibil ity tests by BACTEC-MGIT960 was only 8.5 d and 6.5 d,it was shorter than that o f improved 7H9 medium (20.6 d and 17 d) and improved L-J medium.(30.8 d and 26. 5 d).Indentical proportion of drug susceptibility tests was higher than 90%.Conclusion The fast cultivation and drug susceptibility tests b y BACTEC-MGIT960 is helpful to diagnosis and treatment of patients with pulmona ry tuberculosis,and it is a quick,efficient and relieble method.