深圳特区肾结石流行现况及危险因素分析

Study on the epidemiology and risk factors of renal calculi in special economic zone of Shenzhen city

目的 分析深圳特区肾结石流行现况及危险因素。方法 采用因子分析和线性结构方程模型分析肾结石发病的危险因素 ,并进行模型拟合与评估。结果 男、女性患病率分别为 8.0 0 %和5 .12 %。线性结构模型分析显示 :年龄和性别对肾结石患病的总效应为 0 .4 6 14 ,直接效应为0 .36 0 0 ,间接效应为 0 .10 14。血尿酸、血钙和体重指数、血胆固醇、血糖对患病的直接效应分别为0 .340 0和 0 .32 0 0。文化水平、运动强度和饮食习惯对患病无直接影响 ,但通过一些生化指标和肥胖对患病有间接作用 ,影响效应分别为 - 0 .0 4 16和 0 .1882。结论 性别、年龄、肥胖和高胆固醇、高血糖、高血尿酸、高血钙是肾结石的直接影响因素 ,文化水平、运动和不良饮食习惯与肾结石发病有关。

Objective To study the epidemiological characters and risk factors of renal calculi in Shenzhen for future intervention. Methods Risk factors of renal calculi were analyzed by factor analysis and linear structural relation model, followed by fitting and evaluating the model. Results The prevalence rates of renal calculi were 8.00 % and 5.12 % in males and females. The results of LISEREL showed that the total effect of age and sex affecting the development of renal calculi was 0.461 4 , with directly effect 0.360 0 and indirect 0.101 4 . The direct effects of blood uric acid, blood calcium and body mass index, blood cholesterol, blood sugar were 0.340 0 and 0.320 0 respectively. The indirect effect of education, exercise and dietary habit affected the development of renal calculi through index of biochemistry and obesity, were -0.041 6 and 0.188 2 . Conclusion Sex, age, obesity and high blood cholesterol, high blood sugar, high blood uric acid, high blood calcium were the direct influencing factors to renal calculi. At the same time, education, exercise and dietary habit were also associated with the disease.