SARS病房工作的医护人员血清中特异抗体测定分析

Detection on serum specific antibody of physicians and nurses worked in SARS wards

目的 检测密切接触SARS患者的医护人员血清中SARS病毒IgM及IgG抗体的水平 ,对SARS病毒有无隐性感染作初步调查。方法 分别用酶联免疫吸附法和间接免疫荧光法 (IIFA)检测 2 0 0例正常人 ,2 0 0例在SARS病房工作 1个月的医护人员血清中SARS病毒IgM及IgG抗体的水平。结果 正常人及医护人员血清中未检测到SARS病毒IgM及IgG抗体。结论 不同于普通的流行性传染性疾病 ,SARS病毒可能不具有隐性感染性。

Objective Detection on serum specific IgM or IgG antibodies to SARS associated virus in sera of physicians and nurses worked in SARS wards for one month, and investigate the possibility of subclinical infection of the disease.Methods The serum levels of anti-SARS virus IgM or IgG antibodies of 200 normal subjects, 200 physicians and nurses worked in SARS wards for one month were measured by enzyme linked immunosorbent assay and indirect immunofluorescence assay.Results Serum anti-SARS virus IgM or IgG antibodies were not detected in normal subjects and the clinical personnel.Conclusion SARS isn't like common epidemic infectious diseases and SARS virus probably hadn't the potentiality of subclinical infection.