正畸微种植体支抗对错(牙合)畸形影响分析

Analysis of the Influence of Orthodontic Micro-implant Anchorage on Malocclusion

目的研究正畸微种植体支抗对错(牙合)畸形的影响。方法选择错(牙合)畸形患者作为本次研究对象,并采用"电脑随机法"将100例错(牙合)畸形患者进行分组,主要包括两组,其中观察组实施正畸微种植体支抗治疗;对照组实施传统治疗,分析两组炎症因子水平、牙周细胞MMP-2、MMP-9表达、矫治时间。结果观察组错(牙合)畸形患者TNF-α(165.98±1.24)μg/L、 IL-1β(125.04±1.35)μg/L、IL-6(61.29±1.82)pg/mL水平均低于对照组,P <0.05。观察组错(牙合)畸形患者MMP-2、MMP-9表达较对照组指标更有优势,P <0.05。观察组错(牙合)畸形患者矫治时间(14.24±1.04)个月,短于对照组,差异有统计学意义,P <0.05。结论正畸微种植体支抗在错(牙合)畸形中具有较高应用价值,能够使其牙周炎微环境得到改善,促进牙周组织尽快修复,值得研究。

Objective To study the effect of orthodontic micro-implant anchorage on malocclusion.Methods Patients with malocclusion were selected as the study subjects,and 100 patients with malocclusion were divided into two groups.The observation group was treated with orthodontic micro-implant anchorage.The control group was treated with traditional treatment,the levels of inflammatory factors,the expression of MMP-2 and MMP-9 in periodontal cells,and the time of treatment were analyzed.Results The levels of TNF-α(165.98±1.24)μg/L,IL-1 beta(125.04±1.35)μg/L and IL-6(61.29±1.82)pg/mL in the observation group were lower than those in the control group,P<0.05.The expression of MMP-2 and MMP-9 in the observation group was better than that in the control group,P<0.05.The orthodontic time of malocclusion patients in the observation group was(14.24±1.04)months,which was shorter than that in the control group,P<0.05.Conclusion Orthodontic micro-implant anchorage has high application value in malocclusion,which can improve the microenvironment of periodontitis and promote the repair of periodontal tissue as soon as possible.