对叠氮苯甲酸与β-环糊精的包合作用

Inclusion Compound of β-Cyclodextrin with p-Azidobenzoic Acid

合成了对叠氮苯甲酸与 β 环糊精的包合物 ,并利用红外、热重、核磁和紫外等测试方法进行了详细的表征与研究 .包合后客体化合物的热稳定性有了明显的提高 ,其分解温度提高了 +115℃ ;此外还利用紫外光谱的数据计算了包合反应的平衡常数 ,为 ( 793 3± 192 )L·mol-1.

An inclusion compound of p-azidobenzoic acid with β-cyclodextrin (β-CD) was prepared and characterized by thermogravimetry, IR, 1H NMR and UV spectroscopies. The thermal stability of p-azidobenzoic acid was significantly improved after inclusion, and the decomposition temperature difference between the pure p-azidobenzoic acid and that in conclusion compound was +115 ℃. By using data of UV spectroscopy, the binding constant of the inclusion compound was estimated to be (7933±192) L·mol -1.