维生素E对柯萨奇B_3病毒感染的心肌细胞保护作用的研究

Protective effects of Vitamin E on cardiac muscle cells infected by CoxB_3

目的 探讨维生素E抗柯萨奇病毒及对感染病毒的心肌细胞的保护作用。方法 应用一定浓度的维生素E作用于柯萨奇病毒B3 感染的心肌细胞 ,待病毒对照组细胞病变达 ++++时 ,以MTT法测定细胞存活率 ,应用全自动生化分析仪测定细胞上清液中的心肌酶活性。结果 实验组的细胞存活率明显高于病毒对照组 ,心肌酶活性明显低于病毒对照组。结论 维生素E有一定的抗病毒作用 。

Objective To study the antiviral and protective effects of Vitamin E on cardiac muscle cells.Methods Proper concentration of Vitamin E was added into cardial muscle cells infected by CoxB 3.When cells of virus control group pathologicaly change to CEP(++++),survival rate of cells was detected with MTT,Cardiac Enzyme were detected with full automatic biochemical instruments.Results Cell survival rate of experiment group is much higher than that of virus control group,Cardiac Enzyme activity is lower than that of virus control group.Conclusions Vitamin E has antiviral and protective effect on cardiac muscle cell infected by virus。