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2型糖尿病患者视网膜病变与肾功能关系的临床研究

Clinical Study About the Relationship Between Diabetic Retinopathy and Renal Function in Type 2 Diabetes
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摘要 目的 :观察 2型糖尿病视网膜病变 (DR)与肾功能之间的关系。方法 :通过对 92例不同程度视网膜病变的 2型糖尿病患者进行空腹血糖、餐后 2h血糖、糖化血红蛋白、2 4h尿微量白蛋白、尿素氮、肌酐及双侧眼底镜检查 ,并与 30例不伴视网膜病变的 2型糖尿病患者进行对比分析。结果 :糖尿病伴DRⅢ期及增殖期的空腹血糖、餐后2h血糖、糖化血红蛋白与对照组相比有统计学差异 (P <0 .0 5 ,P <0 .0 1) ,糖尿病出现DR各期的 2 4h尿微量白蛋白与对照组相比有统计学差异 (P <0 .0 1)。结论 :2型糖尿病视网膜病变程度是随着 2 4h尿微量白蛋白增加而加重的 ,提示二者之间密切相关。 Objective:To observe the relationship between diabetic retinopathy (DR)and the renal function in Type 2 Diabetes.Methods:Fasting blood glucose(FBG),blood glucose at 2 hours post dinner(P2BG),Glucohemoglobin (HbA1c),24 hours urinary microalbumin (24 h-UMA), blood urea nitrogen (BUN), serum creatinine (Scr) and bilateral retinal photography were determined in 92 type 2 diabetes with different degree in dibetic retinopathy, and were compared with those in 30 type 2 diabetes without diabetic retinopathy.Results:FBG,P2BG,HbA1C in DRⅢ stage and proliferative retinopathy were significantly different from those in control group(P<0.05,P<0.01,24 h-UMA in each stage of DR was also different from control group(P<0.01).Conclusion:The severity of type 2 diabetes retinopathy is closely linked with the increase of 24 h-UMA.
出处 《中国中西医结合肾病杂志》 2003年第11期647-649,共3页 Chinese Journal of Integrated Traditional and Western Nephrology
关键词 2型糖尿病 视网膜病变 肾功能 糖尿病肾病 尿微量白蛋白 Type 2 Diabetes Diabetic retinopathy Renal function
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参考文献9

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