维生素B_(12)混合溶液治疗放射性直肠炎的疗效观察与护理体会

Observation on Clinical Efficacy of Vitamin B_(12) Mixed Solution for Therapy of Radiation Proctitis and Nursing Experience

目的 运用维生素B1 2 混合溶液治疗放射性直肠炎 ,观察其临床治疗效果。方法 将接受放射治疗出现慢性放射性直肠炎患者 32例分为两组 ,治疗组 (1 8例 )运用维生素B1 2 混合溶液保留灌肠 ,对照组 (1 4例 )运用庆大霉素混合溶液保留灌肠。结果 治疗组治愈 1 4例 ,显效 3例 ,1例有效 ,平均治疗时间 (2 7.8± 2 .4 )d ;对照组无 1例治愈 ,显效 5例 ,有效 6例 ,无效 3例 ,平均治疗时间 (4 0 .4± 3.4 )d。两组治愈率、平均治疗天数差异非常显著 (P <0 0 1 )。结论 运用维生素B1 2 混合溶液治疗放射性直肠炎 ,效果满意 ,值得临床推广应用。

The aim of this study is to evaluate the efficacy of vitamin B 12 mixed solution in the treatment of radiation proctitis.Methods Of 32 patients who suffered from radiation proctitis arising from radiotherapy,18 patients were treated by retention enema with vitamin B 12 mixed solution,and 14 patients with gentamycin sulfate liquid.Results Of the 18 patients treated with Vitamin B 12 mixed solution,14 were cured,with a cure rate of 77.8%,and the mean treatment course was 27.8±2.4 d.No patients receiving gentamycin sulfate treatment were cured (0%),and the mean treatment course was 40.4±3.4 d.There were significant differences in cure rate and mean treatment course between the two groups (P<0 01).Conclusions Vitamin B 12 mixed solution is effective for treating radiation proctitis and worth recommendation.