健康仔猪口服亚硒酸钠后血液硒浓度与抗氧化系统动态变化规律的研究

Studies on the Regularity of Antioxidation and Se Level of Selenium in Piglet Per Os

试验按0 6mg/kgBW单剂量对健康仔猪灌服亚硒酸钠溶液后,系统研究了仔猪血液中硒浓度与抗氧化系统动态变化规律。试验结果表明:健康仔猪体内抗氧化系统随机体硒水平的变化而变化,但与后者相比有一个明显的滞后期。给予一定量的硒后,体内的抗氧化能力并没有立即增强,SOD活力及T AOC均经过较长一段时间后才开始显著上升,而GSH Px活性则是先降低而后又逐渐升高,MDA的变化也明显滞后于硒浓度的变化。说明机体内抗氧化系统与硒水平之间存在着内在的规律性的联系。

In this paper the regularity of its antioxidation in the body of the health piglet were systematically studied in the experiment under conditions that 06mg/kg BW of sodium selenite were respectively used per os as the single dose.The results were as follows:The oxidant defense system in the health piglet varied along with the change of Se level in the body and had an obvious lag time compared with the latter.The antioxidtion was not immediately enhanced when a certain quantity of Se was supplied.Both SOD and TAOC began going up considerably after a longer period but GSHPx was firstly fell down and then increasingly rose up.The change in MDA was apparently later than that in Se density. This showed that there was regular inner link between the oxidant defense system and Se concentration.