摘要
目的 :评价国内灼口综合征疗效研究文献报道的治疗方法的有效性及其研究质量。方法 :通过联合检索中国医学生物资料数据库 (CMB)和中文科技期刊数据库 (VIP) ,获得研究方案为随机对照试验 (RCT ) ,研究对象为灼口综合征患者的论著 ,并依据循证医学方法对其进行分析。结果 :共检索到 47篇论著 ,符合纳入标准的有 11篇。RCT论著数量较少 ,研究质量不高 ,无法进行Meta分析。就目前已有文献而言 ,芦笋精胶囊治疗灼口综合征具有较好的短期疗效。维生素B1和B12 相关神经封闭治疗的效果优于口服维生素治疗。结论 :目前国内灼口综合征疗效研究文献的数量及质量均不能满足临床要求 ,需要更多高质量的研究 。
Objective:To determine the effectiveness of the interve ntion of burning mouth syndrome(BMS) reported by Chinese articles and to assess the quality of the studies by evidence-based medicine. Methods: relevant literatures were searched and identified in Chinese Medical Bio logical Database (CMB) and Chinese Technological Periodical Database (VIP) . Stu dies were selected with following criteria: study design- randomized controlle d trials; participants-patients with BMS. An evidence-based analysis was perfo rmed to the literatures. Results: There were totally 47 articles examined and only 11 of them met the criteria . Meta analysis was not possible due to the low quantity and poor quality, However, as far as the p ublished articles concerned, Lusunjing capsule showed good short-term effect in the treatment and nerve block with vitamin B 1 and B 12 was more effec tive than oral admenistering of vitamin. Conclusion: Th e quantity and quality of the reviewed studies are far from satisfaction and ca n not meet the clinical needs. Further trials of high methodological quality ne ed to be undertaken in order to develop effective treatment of BMS.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2003年第6期601-603,共3页
Journal of Practical Stomatology
关键词
灼口综合征
舌痛症
循证医学
维生素
治疗
Evidence-based medicine
Burning mouth syndrome
Treatm ent outcome