羊膜移植结膜囊再造治疗睑球粘连的临床观察

Reconstruction of conjunctival fornixes by amniotic membrane transplantation for symblepharon

目的 观察和评价不同眼表疾病中羊膜移植结膜囊再造治疗睑球粘连的效果。方法 采用新鲜羊膜移植行结膜囊再造 11例 ( 11眼 )。其中酸、碱、热灼伤及机械损伤所致睑球粘连 6例 ( 6眼 ) ,复发性翼状胬肉睑球粘连 5例 ( 5眼 ) ,其中 2眼眼球活动受限。分别行粘连切除、羊膜移植及结膜囊再造术 ,术后随访 6～ 11月。结果 11例中手术成功形成满意结膜囊8例。局部瘢痕粘连 ,但仍有正常深度结膜囊 2例 ,结膜囊变浅 1例。结论 新鲜羊膜取材方便 ,羊膜移植是行结膜囊再造治疗睑球粘连的有效方法。

Objective To observe and evaluate the clinical outcome of amniotic membrane transplantation(AMT) for conjunctival fornix reconstruction in various ocular surface disease.Methods Conjunctival fornix reconstruction with fresh AMT was performed in various ocular surface diseases in 11 patients and followed up 6-11 months.Results 8 eyes formed satisfied conjunctival fornixes,two eyes have partial adhension but with normal depth fornixes and one failed.Conclusion Fresh amniotic membrane is easy to get,AMT is an effective operation for conjunctival reconstruction.