羊膜移植术在严重眼部碱烧伤中的临床应用

Amniotic membrane transplantation in the treatment of severe ocular alkali burn

目的 评价羊膜移植术治疗严重眼部碱烧伤的效果。方法 采用羊膜移植术治疗严重眼部碱烧伤 2 3例 2 9眼。结果 2 9眼中 2 5眼重建成功 ,术后羊膜固定好 ,角膜局部炎症减轻 ,角结膜逐渐愈合。 4眼术后 4～ 10天内出现羊膜脱落、融解。结论 羊膜移植术可以使碱烧伤的角结膜创面迅速上皮化 ,控制角膜的进一步环死和融解 ,减少新生血管的形成 ,但对角膜水肿、浑浊严重的病例 ,羊膜移植术的效果欠佳。

Objective To evaluate the effect of the severe ocular burn treated by amniotic membrane transplantation.Methods 29 eyes of 23 patients were treated with amniotic membrane transplantation.Results In the 29 eyes of 23 cases,25 eyes were successfully reconstructed,the amniotic membrane fixed up well after the operation,the inflammation of the cornea were alleviated and the cornea-conjunctiva gradually cicatrized.The amniotic membrane in 4 eyes was broken up and dissolved 4-10 days after the operation.Conclusion The amniotic membrane transplantation can make the severe alkaline burned cornea epithelization and prevent further atrophy,dissolution and reduce neovascularization.But to those cases with severe cornea edema and opacity,the effect of the amniotic membrane transplantation is not effective.