膝关节软骨退变的MRI与病理对照研究

MRI of articular cartilage degeneration and correlation with pathology

目的:通过不同MR序列对膝关节软骨病变的检出与病理进行对照比较,总结适于软骨退变的MR检查方法。材料与方法:选择尸体膝关节9只,采用7种不同的序列进行扫描,即:FS3DFAST、FS3DRF-spoiledFAST、3DFAST、3DRF-spoiledFAST、SET1WI、SET2WI、SEPDWI。将各序列发现的病变数目及分级与病理结果进行对照,所有结果采用SPSS软件包进行统计学处理。结果:FS3DFAST及FS3DRF-spoiledFAST发现病变的敏感度为92%和95%,均优于其它MR序列,统计学结果显示与其它各序列比较有统计学显著性差异(P<0.05),而这两个序列的扫描结果之间无统计学显著差异(P>0.05)。结论:FS3DFAST及FS3DRF-spoiledFAST序列是发现软骨病变的敏感序列。

Objective: To compare MR sequences in quantifying cartilage degeneration in osteoarthritis of the knee in vitro with pathology in order to conclude and optimize MR sequences for articular cartilage degeneration. Materials and Methods: Nine cadava knees were imaged with 1.5T MRI system. Seven different MR sequences were performed on each knee. The sequences included: FS 3D FAST, FS 3D RF-spoiled FAST, 3D FAST, 3D RF-spoiled FAST, SE T1WI, SE T2WI, SE PDWI. Then compared the number and degree of lesions in each sequence with pathology results. The statistic analysis was accomplished with SPSS software. Results: The sensitivity of FS 3D FAST and FS 3D RF-spoiled FAST was 92% and 95% respectively. The FS 3D FE sequences were significantly better than other sequencesP<0.05. There were no significant difference between FS 3D FAST and FS 3D RF-spoiled FASTP>0.05. Conclusion: FS 3D RF-spoiled FAST and FS 3D FAST imaging are both accurate for the detection and grading of articular cartilage abnormalities of the knee joint.