IgA肾病的中医治疗经验

Experience on the Treatment of IgA Nephrosis by TCM

IgA肾病是肾小球系膜区以IgA为主的免疫球蛋白沉积的一种原发性肾小球肾炎,临床以发作性肉眼血尿与持续性镜下血尿为主要表现。其病因多为热在下焦,但热有实热与虚热之分,实热者为热盛伤络,迫血妄行;虚热者为阴虚内热,虚火扰络,络伤血溢。其次为脾气亏虚,气不摄血以及久病入络,气滞血瘀,络脉受损。治疗方法主要有清热凉血、养阴清热、益气健脾、活血化瘀等,但宜辨证与辨病相结合,才能提高疗效。

IgA nephrosis is a Kind of primary glomerulonephritis characterized by the sedimentation of immunoglobulin A in mesangium region. Its chief clinical manifestation is paroxysmal macroscopic hematuria and continuous microscopic hematuria. TCM considered that its etiology is heal located in the lower - jiao, and the heat is classified as excess - heat and deficiency - heat. Collaterals are damaged with extravasation in case of excess - heat, and interior heat due to yin - deficiency injures the collaterals leading to hemorrhage in deficiency - heat. Moreever spleen - qi deficient with failure of blood control, and prolonged illness involves the collaterals with qi - stagnation and blood - stasis. The therapeutical principles of heat - clearing, blood - cooling, yin - nourishing, qi - benefiting, spleen - strengthening, blood circulation - activating and blood - stasis - removing should be applied, and TCM syndrome differentiation should be combined with differential diagnosis of disease so as to increase the curative effect.