青年冠心病临床分析

CLINICAL ANALYSIS ON CORONARY HEART DISEASE IN YOUTH

目的 探讨青年冠心病患者的心血管危险因素、冠状动脉病变特点与老年冠心病患者的不同点。方法 对56例青年(≤45岁)冠心病患者和66例老年(>60岁)冠心病患者的临床资料(包括冠状动脉造影结果)进行回顾性分析和比较。结果 青年冠心病组吸烟、大量饮酒、肥胖、心血管病家族史明显多于老年组(P<0.001或P<0.01),男性患者多(P=0.008),甘油三酯高(P=0.001)。老年冠心病组糖尿病多(P=0.034),心血管并发症多。青年组多冠状动脉单支病变(P<0.001),老年组多冠状动脉多支病变(P<0.00]),侧支循环多见于老年组。结论 吸烟、大量饮酒、肥胖、心血管病家族史是青年冠心病患者突出的危险因素,不良的生活饮食习惯和遗传因素促使冠心病提早发生。寻求新的无创检查方法筛选青年冠心病的高危人群,做好预防工作,有利于避免或延迟冠心病的发生。

Objective To explore the differences of risk factors of cardiovascular disease and clinical manifestation of coronary lesions between young(≤45 years) and elderly( >60years) cases with coronary hearts disease (CHD). Methods We retrospectly analyzed the clinical data including results of coronary angiography of 56 young and 66 elderly CHD cases. Results Smoking, heavy drinking, obesity and family history of cardiovascular disease were more common in young cases(P<0. 001 or P< 0.01). There were more male cases and higher triglyceride levels in young group(P = 0. 008, P = 0. 001), more diabetic(P = 0.034)and complications in elderly group. Single - vessel lesions appeared more in young group, multi - vessel lesions and collateral circulations more in elderly group(P<0.001, P<0. 001) . Conclusion Smoking, heavy drinking, obesity and family history of cardiovascular disease are important risk factors for young CHD cases compared with elderly cases. Both bad life style and genetic predisposition can help the development of CHD in youth. It is benefit for the prevention of CHD to explore new non- invasive methods to screen the young with higher risk.