消炎方系列治疗慢性非细菌性前列腺炎的临床研究

Clinical Trials of Antiphlogistic Agent Series in Treating Chronic Nonbacterial Prostatitis

目的 :观察消炎方系列治疗慢性非细菌性前列腺炎 (CNP)的疗效。 方法 :共有 16 0例符合条件的病人参与本研究 ,随机分为A(单纯消炎冲剂 )、B(消炎冲剂 +保留灌肠 )、C(消炎冲剂 +直肠给药 )、D(消炎冲剂 +直肠给药+坐浴熏洗 ) 4组 ,单盲对照 ,持续 8周的临床观察。 结果 :A、B、C、D组治愈率分别为 37.5 %、5 7.5 %、5 2 .5 %、82 .5 % ;总有效率分别为 4 2 .5 %、82 .5 %、77.5 %、92 .5 %。D组与A、B、C组比较 ,治愈率差异有显著性 (P <0 .0 5 ) ;D组与B组比较 ,有效率差异无显著性 (P >0 .0 5 ) ;D组与A、C组比较 ,差异有显著性 (P <0 .0 5 )。 结论 :综合疗法能显著提高CNP的疗效 ,具有清热解毒、活血通瘀之功效 ,消炎方系列制剂是治疗CNP的有效中药。

Objective: To investigate the curative effect of antiphlogistic agent series on treating chronic nonbacterial prostatitis (CNP). Methods: One hundred and sixty patients were randomized into 4 groups for an 8 week clinical observation: group A (oral antiphlogistic medicinal granules only), group B (oral antiphlogistic medicinal granules + retention enema), group C (oral antiphlogistic medicinal granules + rectal), and group D (antiphlogistic medicinal granules + rectally + hip bath). Single blind trials were employed. Results: The curative rates of the 4 groups were 37.5 %, 57.5 %, 52.5 % and 82.5 % respectively, while the total efficacy rates were 42.5 %, 82.5 %, 77.5 % and 92.5 % respectively. Compared with groups A, B and C, the curative rate of group D was significantly higher ( P < 0.05 ). The difference in efficacy rates was slight between groups B and D ( P < 0.05 ), but significant between groups A and C ( P < 0.05 ). Conclusions: Combined treatment therapy can improve the effect of CNP treatment and clear away heat and toxic material. The antiphlogistic agent series, with the effect of motivating blood circulation and removing blood stasis, turned out to be an effective traditional Chinese medicine in treating CNP.