成都地区549例大学生精子质量调查

Investigation on the Sperm Quality of 549 College Students in Chengdu Area

目的 :了解成都地区大学生精子质量现状。 方法 :用计算机辅助精子分析 (CASA)技术 ,检查成都地区 14所高校 5 4 9例志愿学生的精子密度、a级精子、b级精子、精子活率及精子运动功能。以精子密度≥ 2 0× 10 6/ml,a +b级精子≥ 5 0 %或a级精子≥ 2 5 %为参考标准 ,将受试者分为正常组和异常组来统计调查结果 ;同时 ,以精子的密度和活率与国内文献报道的结果进行对比。 结果 :5 4 9例志愿者的精子密度、a +b级精子、a级精子及精子活率分别为(5 0 .90± 2 7.31)× 10 6/ml、(42 .2 1± 15 .38) %、(2 9.4 8± 13.71) %及 (5 6 .4 0± 14 .77) % ,其中正常组 345例(6 2 .84 % ) ,异常组 2 0 4例 (37.16 % )。正常组精子的曲线速度 (VCL)、路径速度 (VAP)及直线速度 (VSL)均大于 2 5μm/s,VCL、VAP、VSL及运动的直线性 (LIN)、运动前向性 (STR)均显著大于异常组 (P <0 .0 1)。异常组中 ,187例精子活力异常 (91.6 7% ) ,39例精子密度异常 (19.12 % ) ,2 2例精子密度和精子活力异常 (10 .78% ) ,未发现无精子症者。 5 4 9例志愿者的精子的密度和活率均低于国内文献报道的结果。 结论 :成都地区大学生精子质量异常的情况比较突出 ,其精子的密度和活率与国内文献报道的结果相比呈下降趋势。

Objective: To evaluate the sperm quality of college students in Chengdu area. Methods: A computer assisted sperm analysis (CASA) was made of the sperm concentration, grade A sperm, grade B sperm, sperm viability rate and movement parameters (VCL, VAP,VSL,LIN,STR) of 549 volunteers from 14 colleges in Chengdu area. The volunteers were devided into normal and abnormal groups according to the criteria (sperm concentration ≥20×10 6 /ml, grade A and B sperm ≥50% or grade A sperm ≥25%). The results were compared with the data reported in China. Results: Among the 549 volunteers, the sperm concentration was ( 50.90 ± 27.31 )×10 6 /ml, grade A and B sperm was ( 42.21 ± 15.38 )%, grade A sperm was ( 29.48 ± 13.71 )%, and the sperm viability rate was ( 56.40 ± 14.77 )%. The volunteers with normal sperm accounted for 62.84 %(345/549) in contrast with abnormal( 37.16 %, 204/549). Among the 204 volunteers with abnormal sperms, there were 187 ( 90.67 %) with abnormal motility, 39( 19.21 %) with abnormal concentration, 22( 10.78 %) with both abnormal concentration and abnormal motility. There were no volunteers without sperm. Among the 345 volunteers with normal sperm, the VCL, VAP and VSL were above 25 μm/s, and the VCL, VAP, VSL, LIN and STR were significantly higher than those of the abnormal group ( P < 0.01 ). Moreover, the sperm concentration and the sperm viability rate in 549 volunteers, including 345 volunteers with normal sperm, were lower than the data reported in China.Conclusions: Due attention should be paid to the sperm quality of the college students in Chengdu area, whose sperm concentration and sperm viability rate have a tendency to decrease.