116例骨转移癌放射治疗止痛效果分析

Radiotherapy for Pain Relief in 116 Cases with Cancer Bone Metastasis

[目的]分析不同分割方式对转移性骨肿瘤放射治疗的止痛效果.[方法]将116例骨转移癌患者分为3组,分别用50Gy/20次、26天,5次/周;28Gy/7次、9～11天,5次/周;24Gy/4次、8～10天,3次/周的不同分割方式进行止痛放疗.[结果]全组病例有效率(CR+PR+MR)为96.6%,3个剂量组的有效率依次为95.5%(21/22),97.5%(77/79),93.3%(14/15).3组之间止痛效果无显著性差异.92%(103/112)的疼痛缓解出现在放疗后1～3周.[结论]对骨转移癌进行局部止痛放疗是一种有效的对症治疗手段,研究的3种分割方式之间无明显疗效差异.

To investigate the efficacy of radiation with various fr actionation schemes for the pain relief in patients with bone metastasis.One hundred and sixteen cases with the bone metastasis were divided into3group s:group1were treated with50Gy/20fractions,26days,5fractions/week;group2,28Gy/7fr actions,9~11days,3fractions/week,respectively.The overall pain re-lief (CR+PR+MR)rate was96.6%.The pain relief rates in1,2,3groups were95.5%(21/22),9 7.5%(77/79),and93.3%(14/15),respectively.There was no significant difference amo ng the three weeks fol-lowing radiation.[Conclusions]Local radiotherapy is an e ffective pain relief measure for bone metastasis.There is no significant differe nce among the three different fractionation schemes for pain relief.