锌对雏鸭外周血T-淋巴细胞的影响(英文)

Effect of Zinc on Peripheral Blood T-lymphocyte in the Duckling

15 0只 1日龄天府肉鸭健雏随机分为 3组 ,分别喂给缺锌 (每千克日粮含 Zn 2 2 .9mg)、对照 (每千克日粮含 Zn10 0 mg)和锌中毒 (每 kg日粮含 Zn130 0 mg)日粮 7周或 4周 ,以酸性 - α-醋酸萘酯酶 (ANAE)染色法观测外周血 T-淋巴细胞的动态变化。结果锌缺乏组和锌中毒组雏鸭外周血 T-淋巴细胞的 ANAE阳性率显著低于对照组 (P<0 .0 1) ,表明锌缺乏或锌中毒可抑制 T-淋巴细胞的生成 ,降低其在外周血中的数量。本试验还对锌缺乏和锌中毒引起的外周血

day-old Tianfu ducklings were divided into three groups,and fed with diets as follows:Zn deficient (22.9 mg Zn per kg diet),controls(100 mg Zn per kg diet) and Zn toxic ((1 300) mg Zn per kg diet) for seven weeks (Zn deficiency,ZD) or four weeks(Zn toxicity,ZT).The ANAE^+ positive ratios of the peripheral blood T-lymphocytes were much lower(P<0.01) in Zn deficient and toxic groups than in the control group.The results showed that Zn deficiency and toxicity would suppress the development of T-lymphocytes and reduce the peripheral blood T-lymphocyte populations.Potential mechanisms underlying these observations are also discussed.