外源基因在大肠杆菌中表达的优化

Expressional Optimization of Heterologous Gene in E.coli

大肠杆菌已经被广泛地应用于表达各种外源基因,但基因的表达受多种因素的影响,现就各种影响因素综述了外源基因表达的优化策略,这将有助于采取有效方法提高外源基因在大肠杆菌中的表达效率.

E.coli has widely been used in expressing a great variety of heterologeous genes,but many factors contribute to influencing the expression.This review summarizes the optimarized expression strategies according to the influencial factors,which will help to take effective measures to improve the expressional efficiency of heterologous genes in E.coli.