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次级淋巴组织趋化因子研究进展 被引量：2

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摘要 次级淋巴组织趋化因子 (secondarylymphoidchemokine ,SLC)是近年新发现的一种趋化因子 ,是一种小分子蛋白质 ,对淋巴细胞、树突状细胞 (dendriticcell,DC)有很强的趋化作用 ,与淋巴细胞归巢和DC向淋巴组织的迁移有密切关系 ,同时还有抗肿瘤免疫效应。本文对SLC的一般生物学特征、基因表达及其免疫学功能作一综述。
作者 梁春敏 叶翠平 叶胜龙
机构地区 复旦大学上海医学院博士研究生 复旦大学上海医学院人体解剖与组织胚胎学系 复旦大学肝癌研究所
出处 《国外医学（免疫学分册）》 2004年第1期15-19,共5页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 国家 8 63基金资助项目 ( 2 0 0 1AA2 1713 1) 复旦大学"985工程"重中之重学科项目 "2 11工程"肿瘤学科建设项目基金资助
关键词 SLC 生物学特征 功能
分类号 R392.11 [医药卫生—免疫学]
  • 相关文献

参考文献23

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同被引文献14

  • 1马飞,孙文欣,张叔人,刘蓉枝,付明,梁肖,张雪艳,林晨.次级淋巴组织趋化因子基因转染对小鼠黑色素瘤细胞生物学特性的影响[J].免疫学杂志,2005,21(5):362-365. 被引量：6
  • 2Rossi D,Zlotnik A.The biology of chemokines and their receptors.Annu Rev Immunol,2000;18(2):217-242.
  • 3Takeuchi H,Fujimoto A,Tanaka M,et al.CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells.Clin Cancer Res,2004;10(7):2351-2358.
  • 4Matsuyoshi H,Senju S,Hirata S,et al.Enhanced priming of antigen-specific CTLs in vivo by embryonic stem cell-derived dendritic cells expressing chemokine along with antigenic protein:application to antitumor vaccination.J Immunol,2004;172(2):776-786.
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  • 6Chengalvala MVR,Lubeck MD,Selling BJ,et al.Adenovirus vectors for gene expression.Curr Opin Biotechnol,1991;2(5):718-722.
  • 7Willimann K,Legler D,Loetscher M,et al.The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7.Eur J Immunol,1998;28(6):2025-2034.
  • 8Cyster J.Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs.J Exp Med,1999;189(3):447-450.
  • 9Gunn M,Kyuwa S,Tam C,et al.Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization.J Exp Med,1999;189(3):451-460.
  • 10Moretta A,Bottino C,Vitale M,et al.Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.Annu Rev Immunol,2001;19(2):197-223.

引证文献2

国外医学（免疫学分册）
2004年 第1期

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