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共刺激分子的新成员—ICOS的研究近况 被引量：2

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摘要 可诱导共刺激分子 (ICOS)是最新发现的共刺激分子家族成员。本文对ICOS的生物学性状、ICOS的功能研究及ICOS在疾病病理机制中的作用等方面的研究近况作一综述。
作者 王健 沈茜
机构地区 第二军医大学长海医院中心实验室 第二军医大学长海医院中心实验室
出处 《国外医学（免疫学分册）》 2004年第1期28-31,共4页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 国家科技部"863"计划项目资助 ( 2 0 0 2AA2 14 0 91)
关键词 ICOS 共刺激分子 免疫
分类号 R392.11 [医药卫生—免疫学]
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参考文献20

  • 1Hufloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cell costimulator structurally and functionally related to CD28. [J]. Nature, 1999,397:263-266.
  • 2Yoshinaga SK,Whoriskey J S, Khare SD, et al.T-cell co-stimulation through BTRP-1 and ICOS. [J] .Nature,1999,402:827-832.
  • 3Mages H W, Hufloff A, Heuck G, et al. Molecular cloning and characterization d murine ICOS and identification of B7h as ICOS ligand. [J] .Eur J Immunol,2000,30 : 1040-1047.
  • 4Beier K C, Hufloff A, Dittrich A M, et al. Inducation, binding specificity and function of human ICOS. [J]. Eur J Immunol,2000,30:3707-3717.
  • 5Haimila K E, Partanen J A, Holopainen P M, et al. Genetic polymorphism of the human ICOS gene. [J]. Immunogeneics,2002,53:1028-1032.
  • 6Temka K,Tsuji T, Flirano d, et al. Identification and characterization of rat AILIM/ICOS, a novel T-cell costimulator molecule, rdated to the CD28/CTLA 4 family. [J]. Biochem Biophys Res Commun,2000,276(1) :335-345.
  • 7Aicher A,Hayden LM, Brady WA,et al. Characterization of human inducible costimulator ligand expression and function. [J]. J Immunol,2000,164(9):4689-4696.
  • 8McAdam AJ, Greenwald RJ, Levin MA, et al. ICOS is critical for CD40-mediated antibody class switching. [J]. Nature, 2001,409(6816) : 102-105.
  • 9Tafurl A, Shahinian A, Bladt F, et al. ICOS is essential for effective T-hdper-cell responses. Nature,2001,409(6816) : 105-109.
  • 10Dong C, Juedes AE,Temann UA, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. [ J ]. Nature, 2001,409(6816) :97-101.

同被引文献33

  • 1真炳攸,张云鹏.成人睾丸和附睾微血管研究[J].海军医高专学报,1994,16(4):257-259. 被引量：2
  • 2吴筱芳,闫晋平.大鼠睾丸微循环的观察[J].山西临床医药,1996,5(1):50-51. 被引量：4
  • 3萨姆布鲁克J 拉塞尔DW 黄培堂 王嘉玺 朱厚础 译.分子克隆实验指南(第3版)[M].北京:科学出版社,2002.2-140.
  • 4Hutloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cellco-stimulator structurally and functionally related to CD28[J]. Nature,1999, 397: 263-266.
  • 5Yoshinaga SK, Whoriskey JS, Khare SD, et al. T-cell co-stimulationthrough B7RP-1 and ICOS[J]. Nature, 1999, 402: 827-832.
  • 6Chambers CA. The expanding world of co-stimulation: the two-signalmodel revisited[J]. Trends Immunol, 2001, 22(4): 217-223.
  • 7Ohsuka A. Microvaseular architecture of the pampiniform plexus- testicular artery system in the rat: a scanning electron microscope study of corrosion casts[J]. Am Anat, 1984, 169(3) : 285-294.
  • 8Erguen S, Davidoff M, Holstein AF. Capillaries in the lamina propria of human seminiferous tubules are partly fenestrated[J]. Cell and Tissue Research, 1996, 286(1): 93-99.
  • 9Cheng CY, Mruk DD. A local autocrine axis in the testes that regulates spermatogenesis[J]. Nature Rev Endocrinol, 2010, 6 (7) : 380-395.
  • 10Mok KW, Mruk DD, Lee WM, et al. A study to assess the as-sembly of a functional blood-testis barrier in developing rat testes [J]. Spermatogenesis, 2011, 1 (3) : 270- 280.

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二级引证文献22

国外医学（免疫学分册）
2004年 第1期

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