摘要
介绍了可用于药物筛选的 3种新的快速高通量筛选方法 ,包括基于反酵母双杂交的筛选系统 ;细胞平台伤的高通量筛选系统以及动物水平的筛选系统。并对其应用原理 。
This article mainly deals with three new dominant plat forms of HTS(High-Throughput Screen) which are fairly useful in drug screen——the reverse yeast two hybrid system, the cell-based screen and the animal platform, including their principles, their application and their advantages together with disadvantages.
出处
《药学进展》
CAS
2004年第1期5-10,共6页
Progress in Pharmaceutical Sciences
基金
国家自然科学基金资助项目 (30 1710 94
30 2 714 97)
关键词
高通量药物筛选模型
酵母双杂交
靶点
受体
HTS (High-Throughput Screen), Yeast Two-Hybridize System, Target, Receptor