血管紧张肽转换酶抑制药在冠心病治疗中的应用

Angiotensin converting enzyme inhibitor in treatment of coronary artery disease

血管紧张肽转换酶抑制药可通过改善心肌供氧耗氧平衡、改善血管内皮功能、抑制交感神经兴奋性、抑制血管平滑肌迁移和增殖、抑制血小板聚集和促进纤维蛋白溶解、抑制低密度脂蛋白氧化修饰、抑制心肌肥厚。

Angiotensin converting enzyme inhibitor may play important role in the treatment of atherosclerosis and coronary artery disease through improving the balance of cardiac oxygen supply and demand improving vascular endothelial function, inhibiting sympathetic activity, inhibiting vascular smooth muscle migration and proliferation, inhibiting platelet aggregation and promoting fibrinolysis, inhibiting low-density lipoproteins oxidation, inhibiting cardiac hypertrophy, and delaying heart remodeling.